产品名称
FN3K Rabbit Polyclonal Antibody
蛋白名称
Fructosamine-3-kinase (EC 2.7.1.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H479
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H479/entry
Mouse Swissprot No.
Q9ER35
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ER35
免疫原
Synthesized peptide derived from human protein . at AA range: 130-210
特异性
FN3K Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],
组织表达
Widely expressed (PubMed:11522682). Expressed in erythrocytes (PubMed:11016445).
功能
function:May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.,similarity:Belongs to the fructosamine kinase family.,subunit:Monomer.,tissue specificity:Expressed in erythrocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.