RM2924

CD22 (18D18) Rabbit Monoclonal Antibody

SIGLEC2; SIGLEC-2

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of human CD22

WB: 1:1000 IHC: 1:200 ICC/IF: 1:20 IP: 1:20

140kDa

95kDa

-20°C/1 year

Rabbit

IgG

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling.

Affinity Purification