产品名称
KRA94 Rabbit Polyclonal Antibody
基因名称
KRTAP9-4 KAP9.4 KRTAP9.4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/85280
Human Swissprot No.
Q9BYQ2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BYQ2/entry
免疫原
Synthesized peptide derived from human KRA94 AA range: 48-98
特异性
This antibody detects endogenous levels of KRA94 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008],
功能
function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 9 family.,subunit:Interacts with hair keratins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
