产品名称
CITE2 Rabbit Polyclonal Antibody
蛋白名称
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99967
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99967/entry
Mouse Swissprot No.
O35740
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35740
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
CITE2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
细胞定位
Nucleus . Colocalizes with EP300 in dot-like structures.
功能
function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.