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CITE2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN1691
产品名称
CITE2 Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
CITED2 MRG1
蛋白名称
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene ID
10370
Human Swissprot No.
Q99967
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99967/entry
Mouse Swissprot No.
O35740
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35740
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
CITE2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
预测分子量
29kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
组织表达
Pancreas,
细胞定位
Nucleus . Colocalizes with EP300 in dot-like structures.
功能
function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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