RM2734

Phospho-PLCG 2 (Tyr1197) (8K1) Rabbit Monoclonal Antibody

FCAS3; APLAID; PLC-IV; PLC-gamma-2

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding Tyr1197 of human PLCG 2

WB: 1:2000 ICC/IF: 1:100 IP: 1:20

148kDa

148kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]

Affinity Purification