产品名称
DUX5 Rabbit Polyclonal Antibody
蛋白名称
Double homeobox protein 5
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96PT3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96PT3/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
DUX5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
double homeobox 5(DUX5) Homo sapiens The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008],
组织表达
Expressed in hepatoma Hep3B cells.
功能
developmental stage:Expressed in fetal tissue.,domain:Homebox domain 2 confers nuclear targeting.,function:Probable transcription activator. Binds the P5 DNA element sequence 5'-GATCTGAGTCTAATTGAGAATTACTGTAC-3'.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and a poly(A) addition signal.,similarity:Belongs to the paired homeobox family.,similarity:Contains 2 homeobox DNA-binding domains.,subcellular location:Actively transported through the nuclear pore complex (NPC).,tissue specificity:Expressed in hepatoma Hep3B cells,.,tissue specificity:Expressed in rhabdomyosarcoma TE671 cells as well as in several other normal and cancer cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
