RM2721

Phospho-Estrogen Receptor alpha (Ser104/Ser106) (9G1) Rabbit Monoclonal Antibody

ER; ESR; Era; ESRA; ESTRR; NR3A1

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding Ser104/Ser106 of human Estrogen Receptor alpha

WB: 1:1000 ICC/IF: 1:50

66kDa

66kDa

-20°C/1 year

Rabbit

IgG

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Affinity Purification