RM2715

Phospho-eIF4EBP1 (Thr37) (4D2) Rabbit Monoclonal Antibody

BP-1; 4EBP1; 4E-BP1; PHAS-I

常规抗体

WB

Human,Mouse

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding Thr37 of human eIF4EBP1

WB: 1:1000

15-20kDa

13kDa

-20°C/1 year

Rabbit

IgG

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]

Affinity Purification