RM2707

Phospho-Caldesmon (Thr753) (18K9) Rabbit Monoclonal Antibody

CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding Thr753 of human Caldesmon

WB: 1:1000 ICC/IF: 1:20-1:100

80kDa

93kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Affinity Purification