产品名称
Phospho-PDGF Receptor beta (Tyr740) (18Q1) Rabbit Monoclonal Antibody
别名
Pdgfr; CD140b; PDGFR-1; AI528809
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic phosphopeptide corresponding to residues surrounding
Tyr740 of mouse PDGF Receptor beta
稀释度
WB: 1:1000 ICC/IF: 1:50
背景介绍
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
