产品名称
Phospho-BubR1 (Thr680) (7L3) Rabbit Monoclonal Antibody
别名
MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic phosphopeptide corresponding to residues surrounding
Thr680 of human BubR1
稀释度
WB: 1:1000 ICC/IF: 1:100 FC: 1:50 IP: 1:20
背景介绍
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]