RM2665

CD27 (8V3) Rabbit Monoclonal Antibody

T14; S152; Tp55; TNFRSF7; S152. LPFS2

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human CD27

WB: 1:1000 IHC: 1:200 ICC/IF: 1:50-1:200 FC: 1:20-1:100

49kDa

29kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Affinity Purification