产品名称
ARL11 Rabbit Polyclonal Antibody
蛋白名称
ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q969Q4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q969Q4/entry
Mouse Swissprot No.
Q6P3A9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6P3A9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5BK71
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
ARL11 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010],
组织表达
Expressed in lung and leukocytes.
功能
disease:Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400].,function:May play a role in apoptosis. May act as a tumor suppressor.,similarity:Belongs to the small GTPase superfamily. Arf family.,tissue specificity:Expressed in lung and leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
