产品名称
Phospho-CD3 zeta (Tyr83) (3W8) Rabbit Monoclonal Antibody
别名
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Tyr83 of human CD3 zeta
稀释度
WB: 1:1000-1:5000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20
背景介绍
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]