RM2498

eIF3B (2Y17) Rabbit Monoclonal Antibody

PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human eIF3B

WB: 1:1000-1:5000 IHC: 1:20-1:50

117kDa

93kDa

-20°C/1 year

Rabbit

IgG

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.

Affinity Purification