产品名称
ELF2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1998
Human Swissprot No.
Q15723
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15723/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69257
Mouse Swissprot No.
Q9JHC9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHC9
免疫原
Synthesized peptide derived from human ELF2 AA range: 80-130
特异性
This antibody detects endogenous levels of ELF2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.
功能
function:Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. Isoform 2 may function in repression of RUNX1-mediated transactivation.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts with the LIM domains of LMO2 (By similarity). Interacts via its N-terminal region with RUNX1.,tissue specificity:Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
