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Phospho-CD3 zeta (Tyr142) (5Z16) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM2367
产品名称
Phospho-CD3 zeta (Tyr142) (5Z16) Rabbit Monoclonal Antibody
别名
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
类别
常规抗体
推荐应用
WB
反应种属
Human
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Tyr142 of human CD3 zeta
稀释度
WB: 1:1000 ICC/IF: 1:50 IP: 1:20
参考分子量
19kDa
预测分子量
19kDa
运输及保存条件
-20°C/1 year
宿主
Rabbit
同种型
IgG
背景介绍
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
纯化
Affinity Purification

Western blot detection of Phospho-CD3 zeta (Tyr142) in Jurkat cell lysates using Phospho-CD3 zeta (Tyr142) antibody(1:500 diluted).

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