产品名称
KDM4D Rabbit Polyclonal Antibody
蛋白名称
Lysine-specific demethylase 4D (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3D) (Jumonji domain-containing protein 2D)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6B0I6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6B0I6/entry
Mouse Swissprot No.
Q3U2K5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3U2K5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941A1A5Q5
免疫原
Synthesized peptide derived from human protein . at AA range: 400-480
特异性
KDM4D Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,
组织表达
Brain,Embryo,Teratocarcinoma,Testis,
功能
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
