产品名称
GKN2 Rabbit Polyclonal Antibody
基因名称
GKN2 BLOT GDDR TFIZ1 UNQ465/PRO813
蛋白名称
Gastrokine-2 (Blottin) (Down-regulated in gastric cancer) (Trefoil factor interactions(z) 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86XP6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86XP6/entry
Mouse Swissprot No.
Q9CQS6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQS6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q29TV8
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
GKN2 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015],
组织表达
Expressed in gastric mucosa.
功能
similarity:Contains 1 BRICHOS domain.,subunit:Interacts with TFF2 (By similarity). Heterodimer with TFF1; disulfide linked.,tissue specificity:Expressed in gastric mucosa.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.