产品名称
BACE2 (8O7) Rabbit Monoclonal Antibody
别名
ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
Recombinant protein of human BACE2
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 IP: 1:20
背景介绍
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]