RM2258

KIAA1967 (6Q5) Rabbit Monoclonal Antibody

DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human KIAA1967

WB: 1:1000 IHC: 1:200 ICC/IF: 1:50 FC: 1:50 IP: 1:20

130kDa

103kDa

-20°C/1 year

Rabbit

IgG

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis.

Affinity Purification