产品名称
TB10B Rabbit Polyclonal Antibody
蛋白名称
TBC1 domain family member 10B (Rab27A-GAP-beta)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q4KMP7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KMP7/entry
Mouse Swissprot No.
Q8BHL3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHL3
免疫原
Synthesized peptide derived from part region of human protein
特异性
TB10B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
TBC1 domain family member 10B(TBC1D10B) Homo sapiens Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010],
组织表达
Brain,Epithelium,Ovary,Placenta,PNS,Teratocarcinoma,Testis,Uterus,
细胞定位
Cytoplasm . In melanocytes, located at the periphery of cells.
功能
function:May act as a GTPase-activating protein.,similarity:Contains 1 Rab-GAP TBC domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
