BD-PN1627

ZN750 Rabbit Polyclonal Antibody

常规抗体

ZNF750

Zinc finger protein 750

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

79755

Q32MQ0

https://www.uniprot.org/uniprotkb/Q32MQ0/entry

Q8BH05

http://www.uniprot.org/uniprot/Q8BH05

Synthesized peptide derived from part region of human protein

ZN750 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

79kD

-20°C/1 year

Polyclonal, Rabbit,IgG

zinc finger protein 750(ZNF750) Homo sapiens This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008],

Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.

Nucleus .

caution:Despite its name, it does not contain a canonical C2H2-type zinc-finger.,disease:Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform [MIM:610227]. Seborrhea-like dermatitis with psoriasiform is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.,tissue specificity:Expressed in the skin, prostate, lungs placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.