产品名称
IFRD1 Rabbit Polyclonal Antibody
蛋白名称
Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O00458
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O00458/entry
Mouse Swissprot No.
P19182
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P19182
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P20695
免疫原
Synthesized peptide derived from human protein . at AA range: 280-360
特异性
IFRD1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],
组织表达
Expressed in a variety of tissues.
功能
function:Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.,similarity:Belongs to the IFRD family.,subunit:Interacts with PSIP1/LEDGF.,tissue specificity:Expressed in a variety of tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
