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LTOR3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN1616
产品名称
LTOR3 Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
LAMTOR3 MAP2K1IP1 MAPKSP1 PRO2783
蛋白名称
Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mitogen-activated protein kinase scaffold protein 1)
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene ID
8649
Human Swissprot No.
Q9UHA4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UHA4/entry
Mouse Swissprot No.
O88653
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88653
Rat Swissprot No.
Q5U204
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5U204
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
LTOR3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
预测分子量
13kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011],
组织表达
Brain,Dendritic cell,Fetal liver,Liver,Lung
细胞定位
Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;
功能
function:Adapter protein that enhances the efficiency of the MAP kinase cascade. Facilitates the activation of MAPK2.,similarity:Belongs to the MAPKSP1 family.,subunit:Interacts with MAP2K1 and MAPK2. Interacts with MORG1 (By similarity). Heterodimer with MAPBPIP.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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