产品名称
TB10B Rabbit Polyclonal Antibody
蛋白名称
TBC1 domain family member 10B (Rab27A-GAP-beta)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q4KMP7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KMP7/entry
Mouse Swissprot No.
Q8BHL3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHL3
免疫原
Synthesized peptide derived from part region of human protein
特异性
TB10B Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
TBC1 domain family member 10B(TBC1D10B) Homo sapiens Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010],
组织表达
Brain,Epithelium,Ovary,Placenta,PNS,Teratocarcinoma,Testis,Uterus,
细胞定位
Cytoplasm . In melanocytes, located at the periphery of cells.
功能
function:May act as a GTPase-activating protein.,similarity:Contains 1 Rab-GAP TBC domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.