RM2033

TPP1 (4M2) Rabbit Monoclonal Antibody

CLN2; GIG1; LPIC; SCAR7; TPP-1

常规抗体

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of human TPP1

WB: 1:1000-1:2000 IHC: 1:20-1:50

61,48kDa

61,35kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]

Affinity Purification