产品名称
Caldesmon (6M5) Rabbit Monoclonal Antibody
别名
CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of human Caldesmon
稀释度
WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:50-1:200 FC: 1:20 IP: 1:20
背景介绍
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
