RM1980

CD86 (9Z10) Rabbit Monoclonal Antibody

B70; B7-2; B7.2; LAB72; CD28LG2

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human CD86

WB: 1:2000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20

75kDa

38kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Affinity Purification