产品名称
STAT1 (3M19) Rabbit Monoclonal Antibody
别名
CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
Recombinant protein of human STAT1
稀释度
WB: 1:1000 ICC/IF: 1:50 FC: 1:200-1:1000 IP: 1:20
背景介绍
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
