RM1970

Ephrin receptor A2 (1K17) Rabbit Monoclonal Antibody

Eck; Myk2; Sek2; Sek-2; AW545284

常规抗体

WB

Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of mouse Ephrin receptor A2

WB: 1:1000 ICC/IF: 1:100 FC: 1:20 IP: 1:20

125kDa

109kDa

-20°C/1 year

Rabbit

IgG

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 signaling pathway.

Affinity Purification