RM1954

Phospho-ATR (Thr1989) (9F2) Rabbit Monoclonal Antibody

FRP1; MEC1; SCKL; FCTCS; SCKL1

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding?Thr1989 of human ATR

WB: 1:1000

301kDa

301kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

Affinity Purification