产品名称
Frzb (10J17) Rabbit Monoclonal Antibody
别名
Frp; Sfrp3; fritz; frzb-1; frezzled
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
Recombinant protein of mouse Frzb
稀释度
WB: 1:1000 ICC/IF: 1:100 FC: 1:20 IP: 1:20
背景介绍
Enables Wnt-protein binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within several processes, including animal organ development; negative regulation of cartilage development; and negative regulation of cell differentiation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (frizzled related protein). [provided by Alliance of Genome Resources, Apr 2022]