RM1885

Cleaved C-terminal GSDMD (11A6) Rabbit Monoclonal Antibody

DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik

常规抗体

WB

Mouse

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of mouse Cleaved C-terminal GSDMD

WB: 1:1000

22kDa

53kDa

-20°C/1 year

Rabbit

IgG

Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D). [provided by Alliance of Genome Resources, Apr 2022]

Affinity Purification