产品名称
MonoMethyl-Histone H3 (Arg2) (6L5) Rabbit Monoclonal Antibody
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic methylpeptide corresponding to residues surrounding?Arg2 of human Histone H3
稀释度
WB: 1:2000 ICC/IF: 1:200-1:1000
背景介绍
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.