产品名称
FA58A Rabbit Polyclonal Antibody
蛋白名称
Cyclin-related protein FAM58A (Cyclin-M)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8N1B3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N1B3/entry
Mouse Swissprot No.
Q8QZR8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8QZR8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q4QQW5
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
FA58A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],
组织表达
B-cell,Blood,Kidney,Lung,
细胞定位
cyclin-dependent protein kinase holoenzyme complex,nucleus,
功能
disease:Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR) [MIM:300707]; also known as STAR syndrome or syndactyly with renal and anogenital malformations.,function:May have a role in cell proliferation.,similarity:Belongs to the cyclin family. Cyclin-like FAM58 subfamily.,subunit:Interacts with SALL1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
