产品名称
S26A9 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/115019
Human Swissprot No.
Q7LBE3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7LBE3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/320718
Mouse Swissprot No.
Q8BU91
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BU91
免疫原
Synthesized peptide derived from human S26A9 AA range: 689-739
特异性
This antibody detects endogenous levels of S26A9 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008],
组织表达
Predominantly expressed in lung at the luminal side of the bronchiolar and alveolar epithelium of lung. To a lower extent, also expressed in pancreas and prostate.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion. Inhibited by ammonium and thiosulfate.,sequence caution:Translated as stop.,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 STAS domain.,tissue specificity:Predominantly expressed in lung at the luminal side of the bronchiolar and alveolar epithelium of lung. To a lower extent, also espressed in pancreas and prostate.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
