RM1748

RRM2B (6I19) Rabbit Monoclonal Antibody

P53R2; MTDPS8A; MTDPS8B

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human RRM2B

WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 FC: 1:20 IP: 1:20

41kDa

41kDa

-20°C/1 year

Rabbit

IgG

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Affinity Purification