RM1745

PCGF6 (8Y9) Rabbit Monoclonal Antibody

MBLR; Rnf134; AI604840; 4933407A11Rik

常规抗体

WB

Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of mouse PCGF6

WB: 1:1000 ICC/IF: 1:20 IP: 1:20

40kDa

40kDa

-20°C/1 year

Rabbit

IgG

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.

Affinity Purification