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Cullin 4A/B (17D4) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM1636
产品名称
Cullin 4A/B (17D4) Rabbit Monoclonal Antibody
别名
SFM2; MRXSC; CUL-4B; MRXHF2; MRXS15
类别
常规抗体
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of human Cullin 4B
稀释度
WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20
参考分子量
88,104kDa
预测分子量
88,104kDa
运输及保存条件
-20°C/1 year
宿主
Rabbit
同种型
IgG
背景介绍
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
纯化
Affinity Purification

Western blot detection of Cullin 4A/CUL-4A+Cullin 4B/CUL-4B in Jurkat,C6,CHO-K1 cell lysates using Cullin 4A/CUL-4A+Cullin 4B/CUL-4B antibody(1:500 diluted).

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