产品名称
Acetyl Coenzyme A carboxylase alpha (5I6) Rabbit Monoclonal Antibody
别名
ACC; ACAC; ACC1; ACCA; ACACAD
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
Recombinant protein of human Acetyl Coenzyme A carboxylase alpha
稀释度
WB: 1:1000-1:2000 IHC: 1:200-1:500 ICC/IF: 1:50 FC: 1:200-1:500 IP: 1:20
背景介绍
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
