产品名称
GSDMD (4O13) Rabbit Monoclonal Antibody
别名
DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
Recombinant protein of mouse GSDMD
稀释度
WB: 1:1000 IHC: 1:1000 FC: 1:500 IP: 1:20-1:50
背景介绍
Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D). [provided by Alliance of Genome Resources, Apr 2022]
