产品名称
DMRT2 Rabbit Polyclonal Antibody (Center)
别名
Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL-2, DMRT2, DSXL2
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
Q9Y5R5
特异性
This DMRT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 357-392 amino acids from the Central region of human DMRT2.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
组织表达
Expressed in testis, kidney and skeletal muscle.
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
功能
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
