产品名称
S39A5 Rabbit Polyclonal Antibody
蛋白名称
Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6ZMH5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZMH5/entry
Mouse Swissprot No.
Q9D856
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D856
免疫原
Synthesized peptide derived from part region of human protein
特异性
S39A5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
组织表达
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
功能
function:May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status.,PTM:Glycosylated.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
