产品名称
ZHX3 Rabbit Polyclonal Antibody
蛋白名称
Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H4I2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H4I2/entry
Mouse Swissprot No.
Q8C0Q2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C0Q2
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q80Z36
免疫原
Synthesized peptide derived from part region of human protein
特异性
ZHX3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed. High expression in kidney. Expressed during osteogenic differentiation.
功能
function:Acts as a transcriptional repressor. Is a regulator of podocyte gene expression during primary glomerula disease.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 5 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX2. Heterodimerization with ZHX1 is a prerequisite for repressor activity. Interacts with NFYA.,tissue specificity:Widely expressed. High expression in kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
