BD-PB4990-CAPN2 Rabbit Polyclonal Antibody (N-Term)-现货抗体产品库武汉枢密脑科学技术有限公司

CAPN2 Rabbit Polyclonal Antibody (N-Term)

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产品基本信息

产品货号

BD-PB4990

产品名称

CAPN2 Rabbit Polyclonal Antibody (N-Term)

别名

Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain, CAPN2, CANPL2

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

存储缓冲液

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.

Human Swissprot No.

P17655

特异性

This CAPN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 10-43 amino acids from human CAPN2.

稀释度

WB~~1:8000

预测分子量

80kDa

运输及保存条件

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

宿主

Rabbit

同种型

Rabbit IgG

背景介绍

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508).

组织表达

Ubiquitous.

细胞定位

Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding

功能

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

期货

现货

All lanes : Anti-CAPN2 Antibody (N-Term) at 1:8000 dilution Lane 1: rat lung lysates Lane 2: C2C12 whole cell lysates Lane 3: A431 whole cell lysates Lane 4: Hela whole cell lysates Lane 5: PC-3 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 80 kDa Blocking/Dilution buffer: 5% NFDM/TBST.