产品名称
RAC2 Rabbit Polyclonal Antibody (C-term)
别名
Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
P15153
特异性
This RAC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-192 amino acids from the C-terminal region of human RAC2.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
组织表达
Hematopoietic specific.
细胞定位
Cytoplasm. Note=Membrane-associated when activated
功能
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
