产品名称
TUT4 Rabbit Polyclonal Antibody
基因名称
ZCCHC11 KIAA0191 TUT4
蛋白名称
Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q5TAX3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5TAX3/entry
Mouse Swissprot No.
B2RX14
Mouse Swissprot Link
http://www.uniprot.org/uniprot/B2RX14
免疫原
Synthesized peptide derived from part region of human protein
特异性
TUT4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011],
细胞定位
Nucleus . Cytoplasm . Cytoplasm, Cytoplasmic ribonucleoprotein granule . Mainly cytoplasmic (PubMed:19703396, PubMed:25480299). Translocates into the cytoplasm following treatment of the cell with LPS (PubMed:16643855). Co-enriched in cytoplasmic foci with MOV10 (PubMed:30122351). .
功能
RNA processing,?RNA catabolic process,?macromolecule catabolic process,?response to organic substance,?miRNA metabolic process,?miRNA catabolic process,?negative regulation of macromolecule metabolic process,posttranscriptional regulation of gene expression,?negative regulation of gene expression,?posttranscriptional gene silencing,?gene silencing,?stem cell maintenance,?gene silencing by RNA,?dsRNA fragmentation,?pre-microRNA processing,?RNA 3'-end processing,?ncRNA processing,?ncRNA metabolic process,?ncRNA catabolic process,posttranscriptional gene silencing by RNA,?gene silencing by miRNA,?gene silencing by miRNA, production of miRNAs,regulation of gene expression, epigenetic,?response to dsRNA,?cellular macromolecule catabolic process,?negative regulation of cell differentiation,?stem cell differentiation,?stem cell development,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.