产品名称
WDR44 Rabbit Polyclonal Antibody
蛋白名称
WD repeat-containing protein 44 (Rabphilin-11)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q5JSH3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5JSH3/entry
Mouse Swissprot No.
Q6NVE8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6NVE8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9R037
免疫原
Synthesized peptide derived from part region of human protein
特异性
WDR44 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
组织表达
Amygdala,Colon endothelium,Endometrial tumor,Epithelium,Teratocarcinoma,Testis,Tong
细胞定位
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Colocalized with RAB11 along microtubules oriented toward lamellipodia. .
功能
function:Downstream effector for RAB11. May be involved in vesicle recycling.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 WD repeats.,subcellular location:Colocalized with RAB11 along microtubules oriented toward lamellipodia.,subunit:Interacts with the GTP-bound form of RAB11 when membrane-associated. Does not bind to other Rab and Rho small G proteins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
