BD-PB4875-STMN2 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

STMN2 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB4875

产品名称

STMN2 Rabbit Polyclonal Antibody (N-term)

别名

Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

存储缓冲液

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.

Human Swissprot No.

Q93045

特异性

This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-69 amino acids from the N-terminal region of human STMN2.

稀释度

FC~~1:25;IHC-P~~1:100~500;WB~~1:1000

预测分子量

21kDa

运输及保存条件

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

宿主

Rabbit

同种型

Rabbit IgG

背景介绍

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).

组织表达

Neuron specific.

细胞定位

Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.

功能

期货

现货

Flow cytometric analysis of SH-SY5Y cells using STMN2 Antibody (N-term)(green) compared to an isotype control of rabbit IgG(blue). BD-PB4875 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded H. liver section using STMN2 Antibody (N-term). BD-PB4875 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

Western blot analysis of lysates from U-87 MG, SH-SY5Y cell line, human brain, mouse brain, rat brain tissue lysate (from left to right), using STMN2 Antibody (N-term)at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.