产品名称
WFDC1 Rabbit Polyclonal Antibody
蛋白名称
WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9HC57
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HC57/entry
Mouse Swissprot No.
Q9ESH5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ESH5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941O70280
免疫原
Synthesized peptide derived from part region of human protein
特异性
WFDC1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
WAP four-disulfide core domain 1(WFDC1) Homo sapiens This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
组织表达
Colon,Kidney,Placenta,Prostate,Stomach,Uterus,
功能
function:Has growth inhibitory activity.,similarity:Contains 1 WAP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.