产品名称
SERBP1 Rabbit Polyclonal Antibody (Center)
别名
Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, SERPINE1 mRNA-binding protein 1, SERBP1, PAIRBP1
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
Q8NC51
特异性
This SERBP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human SERBP1.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
组织表达
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain
细胞定位
Cytoplasm. Nucleus. Cytoplasm, perinuclear region
功能
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:
28695742).
